Searchable abstracts of presentations at key conferences in endocrinology

ea0022p459 | Female reproduction | ECE2010

CAG repeat polymorphism in women with PCOS and healthy controls

Robeva Ralitsa , Dobreva Desislava , Kirilov Georgi , Mechandjiev Tcvetosar , Tomova Analia , Savov Aleksey , Kumanov Filip

The androgen receptor (AR) polymorphism is determined by a variable number of CAG triplets in exon 1 of the AR gene, located on the X chromosome. CAG polymorphism could modulate different hyper- or hypoandrogenic conditions, but its influence on the polycystic ovarian syndrome (PCOS) in different ethnic populations is controversial. Therefore, we investigated the influence of the AR polymorphism on the hormonal factors and clinical signs in 52 women with PCOS and in 41 non-hir...